INS and hypertrophic cardiomyopathy: Pathways were analyzed using the Kyoto Encyclopedia of Genes and Genomes database, and the result indicated that the DEGs included in the red module were enriched in 12 signaling pathways (p < 0.01), including focal adhesion, hypertrophic cardiomyopathy, FoxO, MAPK, Wnt, and insulin signaling pathways (Figure 3d).