Increased numbers of circulating and cardiac neutrophils, identified as CD45+CD11b+Ly6G+, are detectable within 24 h after CVB3 infection and continued to increase in frequency up to 2.5~3 days (55 and 23.6% in circulating and cardiac CD45+ cells, respectively) after infection (Figure 1C). The gene discussed is ITGAM; the disease is infection.