The AUC values of PCT, WBC and hemorrhage for predicting the severity of HFRS were 0.738 (95% CI 0.657–0.820, p < 0.001), 0.706 (95% CI 0.623–0.789, p < 0.001), and 0.640 (95% CI 0.549–0.731, p = 0.004, Figure 1), respectively. The gene discussed is CALCA; the disease is hemorrhage.