It generally showed that cell apoptotic rates and MFI were both lower in GC cells with downregulated SNX1 and higher in GC cells with overexpressed SNX1, indicating that overexpression of SNX1 promoted cell apoptosis although sometimes not significantly (for MKN-1 cells), while knockdown of SNX1 significantly inhibited cell apoptosis (Fig. 6). The gene discussed is SNX1; the disease is gastric cancer.