MARVELD3 and malaria: The variant rs2334880, was one of the novel resistance loci identified and was mapped to 6.4 kb upstream of the MARVEL domain-containing protein 3 gene (MARVELD3; MIM ID*614094), which forms part of multiple tight-junction of epithelial and vascular endothelial cells [9–11] and is strongly associated with severe malaria [12].