Among these genes, PIGY, PIGW, PIGG, PIGM, PIGV, PIGN, PIGL, PIGA, PIGO, PIGT, PIGC, PIGQ, PIGP, PGAP1, PGAP2, and PGAP3 mutations were reported relating to human genetic diseases (Freeze et al., 2014; Supplementary Table 1). The gene discussed is PIGO; the disease is hereditary disease.