By analyzing copy number alterations from The Cancer Genome Atlas (TCGA) data to evaluate the presence of NF1 loss, PDGFRA amplification, and EGFR amplification in human GBM (hGBM) samples when co-incidence of mutations was excluded, we demonstrated that NF1 loss, PDGFRA amplification, and EGFR amplification tend to occur most frequently in MES, PN, and CL hGBMs, respectively (13, 14). Here, EGFR is linked to glioblastoma.