PDGFRA and glioblastoma: By analyzing copy number alterations from The Cancer Genome Atlas (TCGA) data to evaluate the presence of NF1 loss, PDGFRA amplification, and EGFR amplification in human GBM (hGBM) samples when co-incidence of mutations was excluded, we demonstrated that NF1 loss, PDGFRA amplification, and EGFR amplification tend to occur most frequently in MES, PN, and CL hGBMs, respectively (13, 14).