At the 14th day post-infection, there was a decrease switch in the number of CD4+ IL-10+T+ cells observed in WT and ST2−/− mice with an increase in ST2−/− mice (Figures S2G,H in Supplementary Material) and it lined up with the IL-10 amounts in infected joints at all times points evaluated (7–28 days post-infection, Figure S2I in Supplementary Material). The gene discussed is IL10; the disease is infection.