According to the classification “criteria” for APS, the patients had obstetric morbidity only (O-APS; n = 85, 42.5%), thrombotic events (with or without pregnancy morbidity) (T-APS; n = 42, 21%), clinical “non-criteria” manifestations (NC-APS; n = 39, 19.5%) or aPL positivity without any clinical manifestations (aPL carriers; n = 34, 17%). Here, FASLG is linked to autoimmune polyendocrinopathy.