Pathways including Epstein–Barr virus infection, protein processing in endoplasmic reticulum, central carbon metabolism in cancer and steroid biosynthesis were significantly enriched in the PA-N155 host-interacting proteins; DNA replication, RNA transport, mismatch repair, thyroid hormone signaling pathway and cell cycle were enriched in the PA-N182 host-interacting proteins (Figure 3). The gene discussed is TG; the disease is cancer.