While one might argue that this patient may have another unknown autoantibody implicated in the disease course, the fact that our patient has the same haplotype as in previously described cases as well as the presence of IgLON5 antibodies in serum and CSF suggests that the clinical spectrum of IgLON5-associated encephalitis is broader than what is known to date. This evidence concerns the gene IGLON5 and viral encephalitis.