VCAM1 and chronic myelogenous leukemia, BCR-ABL1 positive: Guignabert et al. (2016) suggested increased ROS production, apoptosis, and elevated expression of endothelial adhesion molecules ICAM-1, VCAM-1, and E-selectin in pulmonary artery ECs as underlying mechanisms. Indeed, increased levels of the adhesion molecules were found in the serum of CML patients (Guignabert et al., 2016).