Apart from the discoveries of these physiological roles, considerable studies have been focused on SATB1, given its vital role in gastric cancer (Yuan et al., 2016), breast cancer (Patani et al., 2009; Kobierzycki et al., 2013; Zhang et al., 2015), and CRC (Brocato and Costa, 2015), which suggest its critical role in promoting tumor invasion and metastasis. This evidence concerns the gene SATB1 and colorectal carcinoma.