Several studies have showed that there is an association among androgen, CYP4A and CYP4F expression, 20-HETE synthesis and hypertension (Holla et al., 2001; Nakagawa et al., 2003; Zhou et al., 2005; Wu et al., 2013; Cheng et al., 2014). This evidence concerns the gene CYP4F3 and Hypertension.