CXCL12 and neuroblastoma: The BK-induced responsiveness to SDF-1 could result from lipid rafts formation, a relevant mechanism for the neuroblastoma model (Palacios-Moreno et al., 2015; Ding and Zajac, 2016), since even after 24 h of contact with neuroblastoma lines, BK at various concentrations (10, 30, 100, 300, and 1,000 nM) did not alter CXCR4 expression levels, as evaluated by flow cytometry.