ERN1 and neoplasm: Genes from diverse biological groups were identified to be correlated with the log10IC50 values for BetA, e.g., genes involved in cell cycle regulation and microtubule formation (CHEK2, CDC25C, KIFC1, PTP4A2, CKS1B, CEP170B), signal transduction and transcriptional regulation (GNG5, GNG12, PPP2R4, ERBB3, ZNF652, FAM50A), protein synthesis (NVL, LSM2, ERN1, KANK1), chromatin remodeling (FBL, DNTTIP2, CBX5), cell adhesion (ADAM3A, PTPRJ), tumor suppression (SASH1, WWTR1), ubiquitination and proteasome degradation (AMFR, LITAF).