(Kim et al., 2017) reported that the sensitivity was 85.7% and specificity was 92.2% by an additive prediction model of early leukopenia using NUDT15 R139C in Korean neurological diseases In our study, we calculated the predictability of NUDT15 variant allele for early leukopenia and leukopenia respectively. Here, NUDT15 is linked to Decreased total leukocyte count.