Interestingly, we did not find statistically significant differences in the percentage of Sox2+GFAP+ radial-glia-like astrocytes between the WD group (Mdn = 18% IQR: 16.2–21.75%) and the control group (Mdn = 23% IQR: 20.2–27.7%; U = 25, P = 0.065). This evidence concerns the gene SOX2 and Wilson disease.