We found that the WD group suffered a ~3-fold decrease in the number of BrdU+GFAP+ cells with radial-glia morphology (Mdn = 3.7 cells/mm2 of SGZ area, IQR: 3.2–4.3) as compared with controls (Mdn = 12.6 cells/mm2 of SGZ area, IQR: 10.8–13.5; U = 0; P = 0.004). This evidence concerns the gene GFAP and Wilson disease.