SOX2 and Wilson disease: Our data indicated that the WD group had a significant decrease in the number of BrdU+Sox2+ cells (Mdn = 1.5 cells/mm2 of SGZ area, IQR: 1.5–5.5) respect to controls (Mdn = 28.5 cells/mm2 of SGZ area, IQR: 20.2–37.3; U = 0, p = 0.004).