MATR3 and amyotrophic lateral sclerosis: Mutations in MATR3 account for approximately 1% of total cases of ALS (Johnson et al., 2014; Lin K. P. et al., 2015; Origone et al., 2015; Leblond et al., 2016; Xu et al., 2016; Marangi et al., 2017) and are also causative of autosomal dominant late-onset distal myopathy (Muller et al., 2014).