Moreover, mGluR4 is found in medulloblastomas, colorectal carcinomas and osteosarcomas (Yoo et al., 2004; Chang et al., 2005; Iacovelli et al., 2006; Jiang et al., 2014; Yang et al., 2014; Wang et al., 2016). The gene discussed is GRM4; the disease is colorectal carcinoma.