We found that CaSki expressed relatively low levels of NHERF1 and high levels of ACTN4 compared with HeLa cells (Fig. S4A), whereas CaSki cells, as expected, exhibited higher proliferation ability than HeLa cells (Fig. S4B–D), implying a potential role of NHERF1 in cervical cancer cell proliferation via regulation of ACTN4. Here, ACTN4 is linked to cervical cancer.