DDX39A and neoplasm: To analyze DDX39’s role in HCC development, GSEA analysis was performed to analyze the correlation between DDX39 levels and HCC metastasis, and suggested patients with high-DDX39 levels had high-metastatic ability, patients with low-DDX39 levels had low metastatic ability, DDX39 levels were positive correlation with tumor metastasis (Fig. 2a).