However, there was no significant difference in the anchorage-dependent cell growth/proliferation between KIAA0100-silenced cells and the control cells during the 5-day observation period (Figure 1C), indicating silencing the expression of KIAA0100 had no significant effect on anchorage-dependent cell proliferation/growth in breast cancer cell MDA-MB-231, and also suggesting it might not be directly involved in signal path for the aggressive cancer cell behavior in terms of anchorage-dependent cell proliferation and growth. The gene discussed is BLTP2; the disease is cancer.