Since TCTP, as a cytoplasmic repressor of Na,K-ATPase [45], is known to increase intracellular calcium levels [40], Kim et al. investigated whether opacification of the lens is common in TCTP-overexpressing transgenic C57BL/6 N mice and confirmed that TCTP inhibition of Na,K-ATPase led to a higher incidence (7.38%) of cataracts in TCTP transgenic mice than in the controls (1.47%) (Figure 1). This evidence concerns the gene TPT1 and cataract.