We found that E2F1 regulated genes enriched in ‘cell division’ across all three subtypes, with three target genes in the GO term commonly regulated in lung cancers: CCNF (cyclin F), NCAPH (Non-SMC Condensin I Complex Subunit H), SPAG5 (Sperm Associated Antigen 5). The gene discussed is E2F1; the disease is lung carcinoma.