Furthermore, treatment with αCT1 peptide sensitized human O-6-methylguanine-DNA methyltransferase (MGMT)-deficient and chemotherapeutic agent temozolomide (TMZ)-resistant glioblastoma (GBM) cells and combined treatment with the peptide and TMZ further incur autophagy and apoptosis of TMZ-resistance GMB cells [164]. This evidence concerns the gene MGMT and glioblastoma.