Independently of PDAC molecular classification, one study proposes the classification of pancreatic cancer cell lines based on the level and site of tyrosine phosphorylation (pTyr) of RTKs, potentially identifying three groups of cell lines classified as “low pTyr”, “RTK enriched pTyr” and “mixed pTyr” (on BAIAP2 Y337, PKP3 Y84, PKP2 Y166, CTNND1 Y174, CTNND1 Y 904) [54]. The gene discussed is CTNND1; the disease is familial pancreatic carcinoma.