reported that the positive rates for CEA mRNA expression before and after gastrectomy were 8.8% (5/57) and 33.3% (19/57), respectively.17 Moreover, they demonstrated a close relationship between the presence or absence of CEA mRNA expression and disease recurrence, such as liver metastases.17 The findings of this study suggest that surgical maneuvers enhance the metastatic process from the detachment of primary tumor cells into the systemic circulation in patients with gastric cancer. Here, CEACAM5 is linked to neoplasm.