In our previous study, ATPR was shown to induce G0/G1 phase arrest in gastric cancer cells by downregulating the total expression of 14‐3‐3ε and inducing its nuclear location.12 To further explore the role of ATPR and 14‐3‐3ε on the cell cycle in gastric cancer, a targeted proteomics approach was used to identify the 14‐3‐3ε‐binding proteins in ATPR group and the vehicle group. This evidence concerns the gene YWHAE and gastric cancer.