CFTR and CFTR-related metabolic syndrome/CF screen positive, inconclusive diagnosis: Hypertrypsinogenemic infants identified as having CFTR mutations of varying clinical consequence in conjunction with inconclusive sweat chloride concentration may be assigned a diagnostic place holder known in the United States as CFTR Related Metabolic Syndrome (CRMS) and in Europe as Cystic Fibrosis Screen Positive, Inconclusive Diagnosis (CFSPID).