The first association study of MYH9 with kidney disease was observed in the patients with the giant platelet syndromes, a group of diseases caused by MYH9 mutations and with a spectrum of abnormalities including low platelet count, hearing loss, giant platelets, and cataract may present focal segmental glomerular sclerosis (FSGS) [7]. This evidence concerns the gene MYH9 and focal segmental glomerulosclerosis.