In particular, the combination of ERCC1-118 T/T, ERCC2-751 A/C, and ERCC2-751 C/C was independently associated with low PFS in 166 patients [91] since in post-operative colorectal cancer evolution of 257 Taiwanese patients, the ERCC2-751 A/A and ERCC1-118 T/T genotypes predicted higher incidence of recurrence and worse clinical outcome [92]. The gene discussed is ERCC2; the disease is colorectal cancer.