CD68 and urinary bladder cancer: Although Hanada T, et al [10] reported that higher CD68+ TAMs density significantly correlated with decreased OS (HR = 5.0, 95% CI = 1.98 ~ 12.64), the pooled HR concerning the prognostic role of CD68+ TAMs on OS was 1.01 (95% CI = 1.00 ~ 1.02) (Figure 2A), which indicated the prognostic role of CD68+ TAMs should be cautiously interpreted in bladder cancer patients.