BRCA2 and breast carcinoma: Similarly, for BRCA2 mutation carriers, the estimated penetrance of breast cancer by age 70 years was 48.3% (95% CI: 31.8-68.5%) (Table 2 & Figure 1), which is similar to Korean women, 35% (95% CI: 16-65%)[10] and Chinese women in Beijing, 36.5% (95% CI: 26.7-51.8%) [9] (Table 3).