PHLDA2 and non-small cell lung carcinoma: Moreover, besides the study on the potential tumor suppressor role with negative growth regulation in osteosarcoma [39], those studies generally focused on the expression level and the imprinting status of PHLDA2 in those cancers and no reports on the expression pattern of PHLDA2, its functional role and involved mechanisms of regulation in non-small cell lung cancer have been published.