The results of the IHC analysis of the relationship between MsrB1 expression levels and clinicopathological characteristics showed that MsrB1 expression was correlated with tumor size (P = 0.04, Table 2), age (P = 0.028, Table 2), liver cirrhosis (P = 0.04, Table 2), and Barcelona Clinic Liver Cancer (BCLC) stage (P = 0.03, Table 2). This evidence concerns the gene MSRB1 and cirrhosis of liver.