As indicated in Table 4, the percentage of CD8 T cells (CD8+), NK cells (NK1.1+), macrophages (Mac-3+), and dendritic cells (DC, CD11b+) decreased in mice after 3 months of tumor growth in control group as compared with that in “onset” group, and these decreases were not seen in mice receiving the DI product as no difference in the percentage of these effector cells was seen between onset and extract-treated groups. Here, ITGAM is linked to neoplasm.