ACTA1 and Hepatic fibrosis: These data focus on talking over three aspects: (1) the hBM-MSCs inhibit HSC proliferation and induce apoptosis process in activated HSCs; (2) the positive effect of the hBM-MSCs-downregulated NADPH oxidase pathway influences the levels of PPARγ, α-SMA, and α1(I) collagen in vitro; (3) and the hBM-MSCs play an important role in protecting CCI4-induced liver fibrosis via inhibition of the NADPH oxidase pathway.