In contrast, administration of inulin-type fructans could counteract this HFD-induced GPR43 overexpression and peroxisome proliferator activated receptor γ- (PPARγ-) related adipogenesis in the white adipose tissue of mice [9], suggesting GPR43 expression levels in white adipose tissue might reflect the obesity status in the animal's body. Here, FFAR2 is linked to obesity due to melanocortin 4 receptor deficiency.