EGFR and malignant colon neoplasm: With the high correlation of EGFR and Src expression in primary human colon cancer cells [18] and mammary breast tumours [13], and oncogenic Ras, RasV12, and Src in other human cancer cell lines [20,21], these observations suggest that the contributions of both EGFR-Ras and Src are important in cooperative tumourigenesis.