CCNB1 and neoplasm: On the other hand, intratumoral injection of cyclin-B1-siRNA (1 μg and 5 μg) complexes with MPG-8/chol-MPG-8 at a 1/20 molar ratio and cyclin-B1 siRNA with MPG (5 μg) caused 75% reduction of tumor volume for 1 μg and complete disappearance of tumor for 5 μg of Cyclin-B1-directed siRNA.