BCL2 and neoplasm: The DNA vector-based Bcl-2 siRNA was synthesized under the control of H1 RNA polymerase III (pol III) promoter and mixed with liposome-protamine for evaluating anti-tumor activity of liposome-protamine-psilencer3.1 H1-Bcl-2 complexes (at a ratio of 10:3:1) in a liver cancer mouse model generated via subcutaneous injection of and H22 (liver tumor) cells into male Balb/C mice of 26 ± 2 gm.