VEGFC and non-small cell lung carcinoma: Protein and mRNA expression analysis confirmed that the silencing of VEGF-C gene expression lowered the expression of VEGFR-2, VEGFR-3, CXCR4 and CXCR7 significantly in NSCLC and suppressed the effects of AKT, ERK and p38 signaling pathways, thereby regressing the tumor growth [121].