Radiotherapy response of lung cancer cells was modulated by miR‐214 through regulation of p38 MAPK, apoptosis, and senescence.19 The radiosensitization of lung cancer cells was induced by miR‐122 via targeting BCL‐W and IGF1R.59 Enhanced miR‐15a/16 promoted the radiosensitivity of lung cancer via downregulating the TLR1/NF‐κB pathway.60 Knockdown of miR‐1323 restored radiosensitivity by suppression of PRKDC activity in radiation‐resistant lung cancer cells.61 Our findings added another evidence that miR‐18a‐5p was involved in radiosensitivity in lung cancer cells. Here, TLR1 is linked to lung carcinoma.