Our previous study demonstrated that miR‐18a‐5p was downregulated in CD133+ stem‐like cells in lung cancer compared with CD133− cells.23 Bioinformatic analysis suggested that ataxia telangiectasia mutated (ATM) related to DNA repair and hypoxia inducible factor 1 alpha (HIF‐1, HIF‐1α) related to hypoxia in tumor microenvironment are both potential targets of miR‐18a‐5p. This evidence concerns the gene HIF1A and lung cancer.