KCNQ1OT1 and type 2 diabetes mellitus: In our study, this SNP displayed a similar POE (P-value =3.09E−12) on the CpG probe cg09518720 close to KCNQ1OT1. Kong et al. also found that the SNP rs2334499 showed a parent of origin-specific association with T2D and that the association exhibited a bipolar dominance pattern.