Therefore, in this study we adopted a standardized digital radiography method to measure ATT and found that; 1) ATT was significantly higher in patients with hypercholesterolemia than in the other 2 groups, 2) ATT was positively correlated with serum LDL-C levels and, 3) the serum LDL-C level was an independent risk factor, while the HDL-C and ApoA1 levels were protective factors of ATT. The gene discussed is APOA1; the disease is Hypercholesterolemia.