To date, LC3B expression patterns in cancer are reported predominantly cytoplasmic [38, 39, 44–50], meanwhile other patterns such as large globule (stone) like structure and crescentic (perinuclear) patterns are also observed in oesophageal adenocarcinoma and triple negative breast cancer (TNBC) [39, 48]. This evidence concerns the gene MAP1LC3B and triple-negative breast carcinoma.