Regarding hormone receptor status, the increased trend in CBC in patients with initial hormone receptor-positive BC (Trend 1, APC = 2.3, 95% CI = −7.2 to 12.9; Trend 2, APC = 8.4, 95% CI = 6.9–9.8) was delayed compared with that in patients with initial hormone receptor-negative BC (Trend 1, APC = 44.1, 95% CI = 7–94; Trend 2, APC = 1.5, 95% CI = 0.2–2.7; Figure S2B and Table 2). Here, NR4A1 is linked to breast cancer.