PIGR and infection: The pIgR KO mice showed an increased median survival (P<0.05 by the log-rank Mantel-Cox test) as compared to the C57BL/6 mice (undefined for pIgR KO mice and 9 days for C57BL/6 mice, Fig 3), with 55% of pIgR KO mice and 27% of C57BL/6 mice alive at 16 days post infection.