Head to head meta-analysis results indicated that incidences of increased level of ALT or AST and cataract were not significantly different between ELT and placebo (ALT: RR = 1.39, 95%CI = [0.31, 4.24]; AST: RR = 1.37, 95%CI = [0.55, 3.40]; Cataract: RR = 0.69, CI = [0.24, 1.98], respectively). This evidence concerns the gene GPT and cataract.