IL6 and pulmonary fibrosis: Consistently, in a different mouse model of lung fibrosis (hypochlorite-induced) treated with mouse bone marrow-derived MSC[40], amelioration of fibrosis at day 21 was associated with downregulation of the IL6-IL10-TGFβ axis, further corroborating the hypothesis of a critical involvement of M2 macrophages in lung fibrosis, and the ability of MSC in downregulating those inflammatory stimuli leading to persistent M2 activation and expansion.