ESR1 and adenocarcinoma: (C) Adenocarcinoma tissue sections from JNKWT mice (upper panel) and JNKKO mice (lower panel) were stained with antibodies to (from left to right) estrogen receptor (ER), progesterone receptor (PR), cytokeratins 5 (red) and 8 (green) (CK5 and CK8 respectively), PCNA (Scale bars = 50 μm), and cleaved caspase 3 (Scale bar = 100 μm).